– Chronic cholecystitis

  – Chronic cholecystitis and cholelithiasis

  – Necrotizing cholecystitis

  – Eosinophilic cholecystitis (see comment)

COMMENT: Histologic sections of the gallbladder wall show a dense inflammatory infiltrate composed of primarily eosinophils with scattered lymphocytes and plasma cells. Such findings have been characterized as “eosinophilic cholecystitis,” which is thought to probably not represent a distinct pathological entity, but rather a descriptive diagnosis, as the majority of cases have no known cause of disease association. Nevertheless, some cases have been associated with hypersensitivity reactions, parasitic diseases, and other eosinophilic diseases.  No parasites are identified histologically in this case. Clinical correlation is recommended.



  – Pyloric gland adenoma 

  – Intracholecystic papillary neoplasm with low-grade dysplasia

(or high-grade)

  – Biliary Intraepithelial Neoplasia, Low-grade (BilIN 1/2)

  – Biliary Intraepithelial Neoplasia, High-grade (BilIN 3)

    – Invasive adenocarcinoma


Last updated:  September 16, 2019